Clearview Mono is a rapid, two-step test that provides
accurate results for diagnosing infectious mononucleosis.
Clearly different
Clearview Mono uses a patented, innovative technology to provide
highly sensitive and specific results for infectious
mononucleosis.
- Fast: two-step test provides positive
results in 5 minutes or less
- Easy: CLIA-waived for whole blood;
easy-to-use test
- Reliable: built-in control ensures
accuracy
- Flexible: test can be used with
multiple sample types—whole blood, serum, or plasma
Clearly
better
Clearview Mono provides a rapid, easy solution to the common
challenge of diagnosing infectious mononucleosis.
- Immediate therapy reduces the patient's time of
discomfort
- Minimizes the risk of more serious illness
- Reduces the spread of the virus to others
Clearview® Mono Test Procedure
Add sample.
- 2 drops of whole blood from venipuncture, or full capillary tube
for fingerstick, or
- 1 drop serum or plasma.
Add Buffer. Follow sample with 1 drop of Buffer
solution.
Read result in 5 minutes. For full
instructions, see package insert.
About Mono
Infectious mononucleosis (commonly called "mono") often produces
symptoms of fever, sore throat, and swollen lymph glands. The name
infectious mononucleosis refers to the appearance of infected white
blood cells, as they appear to have a grossly distorted single
nucleus, together with an increase in the number of
monocytes.1
Mono is caused by Epstein-Barr virus (EBV), which is a member of
the herpesvirus family and one of the most common human viruses. As
many as 95% of adults between 35 and 40 years of age have been
infected with EBV sometime during their lives.1
Mono is sometimes referred to as the "kissing disease" because
transmission of EBV requires contact with the saliva of an infected
person. However, EBV is also found in the saliva of healthy people;
in fact, these people can carry and spread the virus intermittently
for life.2
Diagnosis of mono is based on the evaluation of characteristic
clinical symptoms and serologic changes. Serologic diagnosis of
mono can be based on the detection of heterophile and EBV-specific
antibodies.3-5
References
- Davidsohn I. Serological diagnosis of infectious mononucleosis.
JAMA. 1937;108(4): 289-295.
- Centers for Disease Control. National Center for Infectious
Diseases. Epstein-Barr Virus and Infectious Mononucleosis.
Available at: http://www.cdc.gov/ncidod/diseases/ebv.htm.
Accessed March 24, 2004.
- Evans AS, Niederman JC, Cenabre LC, West B, Richards VA. A
prospective evaluation of heterophile and Epstein-Barr
virus-specific IgM antibody test in clinical and subclinical
infectious mononucleosis: Specificity and sensitivity of the tests
and persistence of antibody. J Infect Dis.
1975;132(5):546-554.
- Fletcher MA, Woolfolk BJ. Immunochemical studies of infectious
mononucleosis. Isolation and characterization of heterophile
antigens from hemoglobin-free stroma. J Immunol.
1971;107(3):842-853.
- Khanna R, Burrows SR, Moss DJ. Immune regulation in
Epstein-Barr virus-associated diseases. Microbiol Rev.
1995;59:387-405.