TOX A/B QUIK CHEK^® has a larger sample well to make testing for C. difficile toxins A and B fast, easy, accurate, and clean.

Easy to Use

• A larger sample well means neater, quicker placement.
• Novel patent-pending technology smoothly disperses sample within the device.
• The chance of clogging is minimized, greatly reducing unwanted spillovers.

Easy to Read

• Two lines mean C. difficile toxin A/B is present
• Internal control line validates the QC result in the same reaction window

Highly Accurate

• >90% sensitivity*
• >99% specificity*

TOX A/B QUIK CHEK Testing Procedure

Download sample Procedure Card

About C. difficile

Clostridium difficile is a gram-positive, spore-forming anaerobic bacterium. C. difficile is the leading cause of diarrhea outbreaks or C. difficile-associated disease (CDAD) in hospitals, infirmaries, and elderly care units. CDAD is usually caused by antibiotic or chemotherapy disturbing the normal balance of the gut flora.¹ Virtually any antibiotic is capable of causing the condition and studies have shown reduced antibiotic prescription levels can significantly reduce CDAD cases.² Outbreaks in nosocomial environments are difficult to control since the bacteria produces spores that are difficult to eradicate.²

C. difficile has been identified as the organism responsible for toxin production.³ C. difficile produces two large molecular weight toxins, designated A and B. Toxin A is considered to play a more important role in the etiology of CDAD.⁴ The toxins produce symptoms in CDAD patients, which can range from mild diarrhea to pseudomembranous colitis (PMC). PMC manifests as adherent yellowish-white plaques on the intestinal mucosa. Rapid diagnosis of C. difficile is therefore important in order to treat patients and prevent spread of the disease.²

References

1. Hamm L. Clostridium difficile. Pediatr Pharm. 2000;6(6).
2. McNulty C, Logan M, Donald IP, et al. Successful control of Clostridium difficile in an elderly care unit through use of a restrictive antibiotic policy. J Antimicrob Chemother. 1997; 40:707-711.