Clearview Mono is a rapid, two-step test that provides accurate results for diagnosing infectious mononucleosis.

Clearly different

Clearview Mono uses a patented, innovative technology to provide highly sensitive and specific results for infectious mononucleosis.

• Fast: two-step test provides positive results in 5 minutes or less
• Easy: CLIA-waived for whole blood; easy-to-use test
• Reliable: built-in control ensures accuracy
• Flexible: test can be used with multiple sample types—whole blood, serum, or plasma

Clearly better

Clearview Mono provides a rapid, easy solution to the common challenge of diagnosing infectious mononucleosis.

• Immediate therapy reduces the patient's time of discomfort
• Minimizes the risk of more serious illness
• Reduces the spread of the virus to others

Clearview Mono Test Procedure

Add sample.
- 2 drops of whole blood from venipuncture, or full capillary tube for fingerstick, or
- 1 drop serum or plasma.

Add Buffer. Follow sample with 1 drop of Buffer solution.

Read result in 5 minutes. For full instructions, see package insert.

About Mono

Infectious mononucleosis (commonly called "mono") often produces symptoms of fever, sore throat, and swollen lymph glands. The name infectious mononucleosis refers to the appearance of infected white blood cells, as they appear to have a grossly distorted single nucleus, together with an increase in the number of monocytes.¹

Mono is caused by Epstein-Barr virus (EBV), which is a member of the herpesvirus family and one of the most common human viruses. As many as 95% of adults between 35 and 40 years of age have been infected with EBV sometime during their lives.¹

Mono is sometimes referred to as the "kissing disease" because transmission of EBV requires contact with the saliva of an infected person. However, EBV is also found in the saliva of healthy people; in fact, these people can carry and spread the virus intermittently for life.²

Diagnosis of mono is based on the evaluation of characteristic clinical symptoms and serologic changes. Serologic diagnosis of mono can be based on the detection of heterophile and EBV-specific antibodies.^3-5

References

1. Davidsohn I. Serological diagnosis of infectious mononucleosis. JAMA. 1937;108(4): 289-295.
2. Centers for Disease Control. National Center for Infectious Diseases. Epstein-Barr Virus and Infectious Mononucleosis. Available at: http://www.cdc.gov/ncidod/diseases/ebv.htm. Accessed March 24, 2004.
3. Evans AS, Niederman JC, Cenabre LC, West B, Richards VA. A prospective evaluation of heterophile and Epstein-Barr virus-specific IgM antibody test in clinical and subclinical infectious mononucleosis: Specificity and sensitivity of the tests and persistence of antibody. J Infect Dis. 1975;132(5):546-554.
4. Fletcher MA, Woolfolk BJ. Immunochemical studies of infectious mononucleosis. Isolation and characterization of heterophile antigens from hemoglobin-free stroma. J Immunol. 1971;107(3):842-853.
5. Khanna R, Burrows SR, Moss DJ. Immune regulation in Epstein-Barr virus-associated diseases. Microbiol Rev. 1995;59:387-405.