The BioStar Acceava Mono II test provides superior performance for the diagnosis of Mononucleosis with a simple procedure that provides an answer in 5 minutes. Side-by-side evaluations with competitive products will convince you of this test’s performance. These attributes enable you to deliver improved patient care with a test that fits your staffing requirements.

Easy to Use

• One product available for both CLIA-Moderate and Waived labs.
• More sensitive than other leading rapid mono tests
• Walk-away Flexibility / Room Temperature Storage
• Environmentally Friendly Packaging (Minimal Plastic Waste)
• CLIA Non-waived for Serum, Plasma or Whole Blood Specimens
• CLIA Waived for Whole Blood Specimens Only

Further Benefits of the Acceava Mono II test

• Cost-Effective Diagnosis of Mononucleosis
• Affordably priced for any setting
• Rapid, flexible procedure reduces office staff hands-on time and follow-up activities

Acceava Mono II Test Procedure

Add sample to tube.
- 2 drops of whole blood from venipuncture or full capillary tube for fingerstick or
- 1 drop serum or plasma.

Add Buffer. Follow sample with 2 drops of Buffer solution.

Place Test Strip into Sample Tube.

Read result in 5 minutes. For full instructions, see package insert.

About Mono

Infectious mononucleosis (commonly called "mono") often produces symptoms of fever, sore throat, and swollen lymph glands. The name infectious mononucleosis refers to the appearance of infected white blood cells, as they appear to have a grossly distorted single nucleus, together with an increase in the number of monocytes.¹

Mono is caused by Epstein-Barr virus (EBV), which is a member of the herpesvirus family and one of the most common human viruses. As many as 95% of adults between 35 and 40 years of age have been infected with EBV sometime during their lives.¹

Mono is sometimes referred to as the "kissing disease" because transmission of EBV requires contact with the saliva of an infected person. However, EBV is also found in the saliva of healthy people; in fact, these people can carry and spread the virus intermittently for life.²

Diagnosis of mono is based on the evaluation of characteristic clinical symptoms and serologic changes. Serologic diagnosis of mono can be based on the detection of heterophile and EBV-specific antibodies.^3-5

References

1. Davidsohn I. Serological diagnosis of infectious mononucleosis. JAMA. 1937;108(4): 289-295.
2. Centers for Disease Control. National Center for Infectious Diseases. Epstein-Barr Virus and Infectious Mononucleosis. Available at: http://www.cdc.gov/ncidod/diseases/ebv.htm. Accessed March 24, 2004.
3. Evans AS, Niederman JC, Cenabre LC, West B, Richards VA. A prospective evaluation of heterophile and Epstein-Barr virus-specific IgM antibody test in clinical and subclinical infectious mononucleosis: Specificity and sensitivity of the tests and persistence of antibody. J Infect Dis. 1975;132(5):546-554.
4. Fletcher MA, Woolfolk BJ. Immunochemical studies of infectious mononucleosis. Isolation and characterization of heterophile antigens from hemoglobin-free stroma. J Immunol. 1971;107(3):842-853.
5. Khanna R, Burrows SR, Moss DJ. Immune regulation in Epstein-Barr virus-associated diseases. Microbiol Rev. 1995;59:387-405.