Our ELISA products for autoimmune testing feature single-well ANA screen and ENA screen ELISAs, as well as specific reflex tests including dsDNA, and 6 individual ENA kits: Sm, Sm/RNP, SS-A (Ro), SS-B (La), Scl-70 and Jo-1. In addition, our autoimmune ELISA family includes a full line of products for Cardiolipins (IgA, IgG, IgM), Thyroglobulin, Thyroid Microsomal, MPO, PR3, Rheumatoid Factor and the new anti-CCP ELISA, a highly specific assay for rheumatoid arthritis.

Autoimmune Disease Kits

ANCA Screen II Antinuclear Antibody (ANA) Screen Cardiolipin New! CCP dsDNA - IgG, M II ENA II Gliadin Histone Jo-1 II Mitochondria

Myeloperoxidase (MPO) II Proteinase3 (PR3) II Rheumatoid Factor II Ribosomal P Scl-70 II Sm II Sm/RNP II SS-A (Ro) II SS-B (La) II Thyroglobulin II Thyroid Microsomal II

Featured Product

DIASTAT™ Anti-CCP

Misdiagnosis of rheumatoid arthritis (RA) has major medical and cost implications. Researchers investigating a clinical model for the best early diagnosis of RA reported that the strongest association with persistent arthritis was found for the criteria of symptom duration and anti-CCP positivity. The group also found that the overall discriminative ability of a model without the anti-CCP test was significantly lower than the model with the anti-CCP test.¹

A new highly sensitive and specific second-generation peptide-based test, DIASTAT Anti-CCP* is an ELISA based on the detection of autoantibodies against the cyclic citrullinated peptide (CCP) containing modified arginine residues in human serum or plasma. Enabling early and accurate diagnosis of RA, the Anti-CCP assay provides an additional tool in the diagnosis and management of patients with RA.

Features include:

• Diagnosis of RA in early synovitis patients
• Differentiation of RA from other inflammatory arthritides
• Differential diagnosis of RA from other connective tissue diseases such as erosive systemic lupus erythematosus
• Confirmation of diagnosis in seronegative RA
• Potential to identify patients who will develop a more severe form of RA at disease onset
• Potential to monitor therapeutic effectiveness

References
1. Visser H, et al. How to diagnose rheumatoid arthritis early. Arthritis Rheum 2002: 46(2):357-356.

* Manufactured by Axis-Shield for Inverness Medical Professional Diagnostics, a member of the Inverness Medical family.

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